Published in IJCP
May 2018
NEUROLOGy
Lance-Adams Syndrome: A Rare Case of Post-hypoxic Myoclonus, Developing After a Snake Bite
May 04, 2018 | Meet M Thacker, Manish N Mehta
Nephrology
Lance-Adams syndrome (LAS) is a rare complication of a successful cardiopulmonary resuscitation (CPR) and is often
accompanied by post-hypoxic action myoclonus. Less than 200 cases have been reported in medical literature till date.
A 50-year-old female presented to the Emergency Department in a state of unconsciousness. Urgent intubation and CPR
resulted in stabilization of vitals over a period of few days. On regaining consciousness, the patient developed myoclonus,
which was characteristically present only on activity and absent at rest or during sleep. This action myoclonus was troublesome
to the patient and interfering in the day-to-day activities of the patient. Patient was started on a combination therapy with
levetiracetam and clonazepam, which resulted in marked diminution of myoclonus over a period of 15-20 days. Though LAS
is a rare complication, proper diagnosis and prompt management may significantly reduce the morbidity and improves the
quality-of-life.
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