A 7-day-old female infant born of full-term normal delivery was referred for evaluation of a systolic murmur in left lower parasternal region. Electrocardiogram (ECG) revealed P-pulmonale with right axis deviation and prominent RS configuration in lead V1 (Fig. 1). Echocardiography revealed hypertrophy of right ventricle with a systolic turbulent jet between apex and main cavity of right ventricle (Fig. 2). Continuous wave Doppler evaluation of the jet revealed a systolic gradient of 65.4 mmHg (Fig. 3).