Published in IJCP
To Study the Clinical Outcome of Cardiorenal Syndrome in a Tertiary Care Hospital of Bihar
June 04, 2018 | Jyoti Prakash, Kk Singh
Background: Cardiorenal syndrome (CRS) is defined as disorders of heart and kidney whereby acute or chronic dysfunction in
one organ may induce acute or chronic dysfunction of the other. The exact mechanism of CRS is complex and multifactorial.
Objective of the study: To identify and categorize various patients admitted with CRS into different subtypes and assess the
clinical outcome at discharge and 3 months. Material and methods: We took 50 patients of CRS admitted in ICU of Medicine
Department, Darbhanga Medical College and Hospital (DMCH), Laheriasarai, Darbhanga, Bihar. Outcome was addressed
as favorable for stable patients at discharge and 3 month follow-up, whereas unfavorable for patients who expired or were
put on hemodialysis. Results: Out of 50 patients, 30 patients (60%) were males, with mean ages of males and females being
65.15 and 66.48 years, respectively. Majority of patients had type 1 CRS (44%), followed by type 4 (28%), type 2 (24%) and
type 5 (4%). There were no patients with type 3 CRS. At the end of the study, 25 (50%) patients were stable, 12 (24%) required
dialysis and 13 (26%) patients expired. Conclusion: CRS occurs in all age groups, more commonly in elderly subjects, with
male preponderance. CRS 1 is more prevalent than CRS 4. Prognosis was unfavorable in CRS 1, CRS 4 and CRS 5, bad
prognostic factors being pre-existing renal impairment, anemia, decreased glomerular filtration rate (GFR) and decreased
ejection fraction. Sepsis was the predominant cause of death in patients with CRS 5.