Published in IJCP July 2018
Vitamin D Deficiency - A Reversible Cause of Proximal Myopathy: A Case Report
July 05, 2018 | Subhash Meel, Sameer Aggarwal, Deepak Jain, Hk Aggarwal, Rahul Chauda, Promil Jain

A 22-year-old married Hindu female, vegetarian, with lower socioeconomic status, presented with an insidious onset progressive bilateral lower limb symmetrical proximal muscle weakness without sensory and bladder and bowel involvement, from last 2 years. Bone scan reports were suggestive of mineral and bone disease. Vitamin D deficient osteomalacia was diagnosed based on elevated serum alkaline phosphatase levels, raised intact parathyroid hormone levels, decreased 25-hydroxyvitamin [25(OH)D] levels. Patient's symptoms improved after oral active vitamin D and calcium administration. The present case highlights the importance of considering vitamin D deficiency in patients presenting with musculoskeletal symptoms and a routine evaluation for vitamin D deficiency should be considered in all patients.