Published in IJCP
October 2018
ENDOCRINOLOGY
Posology of Antidiabetic Drugs and Insulins: A Review of Standard Textbooks
October 04, 2018 | Garima Bhutani, Sanjay Kalra
Objectives: The aim of this bibliographic review is to assess whether standard pharmacology, endocrinology and diabetology
textbooks adequately mention the details regarding timings of administration, frequency and dose of various oral and
injectable antidiabetic drugs. Material and methods: Four standard textbooks of pharmacology, two of diabetology and
three of endocrinology were assessed for the published information regarding dose, timing and frequency of antidiabetic
drugs. Results: Various omissions and contraindications were found in the coverage of glucose-lowering drugs in standard
textbooks. Proper timing and frequency of administration of sulfonylureas, thiazolidinediones, SGLT2 inhibitors, GLP
receptor agonists and DPP-4 inhibitors have been omitted in majority of the textbooks. Conclusions: This article stresses
upon the need of a uniform source of information for providing adequate and standardized knowledge regarding timing,
frequency and dose of antidiabetic drugs.
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